Recombinant CHO Lysosomal Acid Lipase (LAL; NCBI XP_035297776.1) is expressed in CHO cells with a 6xHIS tag and purified to >95% purity. LAL appears at ~55 kDa under reducing conditions and is quantified by A280. As a lipid‑metabolizing lysosomal enzyme, LAL can co‑purify with biologics and contribute to product degradation during purification or storage. This high‑quality recombinant antigen provides a reliable standard for ELISA development, antibody validation, and HCP profiling. Its CHO‑derived structure ensures biological relevance for impurity monitoring and process optimization. A valuable tool for teams studying lipid‑processing enzymes, assessing LAL‑related risks, or refining HCP detection workflows.